The Duchy of Urbino was a small state in north-eastern that was eventually annexed by the Papal States in 1625. It appears that Sephardic Jews refugees from Papal persecution in Ancona may have come to the city of Pesaro in 1555. The city’s archives are today in the Archivio di Stato di Pesaro, Sezione di Urbino. http://aspesaro.beniculturali.it/?it/152/sezione-di-urbino
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Sephardic Jewish Genealogy – Family History of the Spanish and Portuguese Jewish diaspora